SSIS 2005 Business Intelligence
Unable to instantiate XML DOM document, please verify that MSXML binaries are properly installed and registered.
Other variations are Failed to save package file “.dtsx” with error 0x8002801D “Library not registered.”
The reason you see this error is because MSXML got corrupted.
The fix is
1. Close Studio / Business Intelligence
2. Download Latest MSXML 4.0 (sp3) as of today.
3. Install it. Done
2a. Some cases you may need to install MSXML 6.0.